Haematological implications of folate food fortification

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Haematological implications of folate food fortification.

Reports from some Western countries indicate that mandatory folate food fortification (FFF) has substantially reduced the prevalence of folate deficiency, leading to calls for folate testing following FFF to be limited to specific indications such as macrocytic anaemia. This is premature for low-income countries, where folate deficiency is predominantly the result of poor intake coupled with th...

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Folate status of women in Toronto: Implications of folate fortification and supplementation.

OBJECTIVES To assess the percentage of women of childbearing age with suboptimal levels of folate for protecting against neural tube defects (<906 nM), and assess folate status among the elderly. METHODS A total of 1,035 anonymous blood samples from a centralized clinical laboratory, with a catchment area across the Greater Toronto Area, were assessed for red blood cell (RBC) folate concen...

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Folate fortification: enough already?1,2

The Food and Drug Administration mandated the folate fortification of grain products in the United States by January 1998. The primary driving force behind this policy was the recognition that periconceptional folate supplementation in addition to normal dietary folate intake significantly reduced the incidence of neural tube defects (NTDs), one of the most common birth defects (1, 2). Food for...

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Folate and neural tube defects: The role of supplements and food fortification.

Periconceptional folic acid significantly reduces the risk of neural tube defects. It is difficult to achieve optimal levels of folate by diet alone, even with fortification of flour, especially because flour consumption in Canada is slightly decreasing. Intermittent concerns have been raised concerning possible deleterious effects of folate supplementation, including the masking of symptoms of...

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Vitamin food fortification today

Historically, food fortification has served as a tool to address population-wide nutrient deficiencies such as rickets by vitamin D fortified milk. This article discusses the different policy strategies to be used today. Mandatory or voluntary fortification and fortified foods, which the consumer needs, also have to comply with nutritional, regulatory, food safety and technical issues. The 'wor...

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ژورنال

عنوان ژورنال: South African Medical Journal

سال: 2013

ISSN: 2078-5135

DOI: 10.7196/samj.7022